We have been following the writings and case studies of a number of hair restoration surgeons across the country that are claiming that they can effect genuine hair regeneration from dormant follicles through the combination of two medical therapies: PRP (Platelet Rich Plasma) Injections and a product called ACell MatriStem. Acell MatriStem is “porcine urinary bladder matrix,” derived from pig bladder cells, that has proven to be very helpful in wound healing. Wound healing has been at the forefront of research into hair cloning and hair follicle regeneration.
At the 19th annual conference of the International Society of Hair Transplant Surgeons, Dr. Gary Hitzig presented evidence that Acell “attacts” adult stem cells to a “wound” and converts them into the progenitor cells that, in the case of hair follicles, actually grow hair. So, the idea is to combine Acell with large amounts of adult stem cells taken from the patient’s own body — which is where the Platelet Rich Plasma (PRP) comes in — and then to inject this into the thinning hair areas of the scalp. The hope is that it will send signals to the adult stem cells lurking in the dormant hair follicles and, in essence, wake them up.
At McGrath Medical we have been reviewing the research and conferring with colleagues. In early 2012 Dr. McGrath began treating select patients with a combination of ACell plus Platelet Rich Plasma. The results have been very encouraging and we are expanding treatment in combination with hair transplant surgery.
Below is a female patient with diffuse alopecia throughout the top of the scalp and 6 months after injection therapy. The patient’s hair has thickened significantly.
ACell’s MatriStem® technology is a naturally occurring, non-crosslinked, completely resorbable, acellular material. MatriStem devices are unique from other scaffold technologies in that they fundamentally change healing by triggering abundant new blood vessel formation and recruiting numerous cell types to the site of injury. It appears that these cells, including progenitor cells, have the potential to differentiate into numerous types of site specific tissues. During the healing process, the scaffold is degraded and completely resorbed, leaving new tissue where scar tissue would normally be expected. This proprietary UBM scaffold technology can be used in a broad range of medical applications such as wound care, general surgery, gastrointestinal surgery, urology and plastic and reconstructive surgery.
More before and after ACell + PRP Hair Regrowth Injection Therapy results.